Large plaques are formed by coalescence of the smaller lesions. Different types of papules are different colors. The duration of thi… Bijlsma, in Clinical Immunology (Fourth Edition), 2013. Aging leads to skin atrophy, including subcutaneous lipoatrophy, striae atrophicae Results from loss of epidermis, dermis or both. Skin thinning and ecchymoses are common adverse events with GCs, even at low doses. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B978032301198350005X, URL: https://www.sciencedirect.com/science/article/pii/B9780702031434100047, URL: https://www.sciencedirect.com/science/article/pii/B9780323612111000450, URL: https://www.sciencedirect.com/science/article/pii/B9780323316965000802, URL: https://www.sciencedirect.com/science/article/pii/B9781437704129000137, URL: https://www.sciencedirect.com/science/article/pii/B9780323044042100879, URL: https://www.sciencedirect.com/science/article/pii/B9780723436911001008, URL: https://www.sciencedirect.com/science/article/pii/B9780702068966000867, URL: https://www.sciencedirect.com/science/article/pii/B9781455725014000072, URL: https://www.sciencedirect.com/science/article/pii/B9780323316965000607, Lookingbill and Marks' Principles of Dermatology (Fifth Edition), 2013, Clinical and Pathologic Findings with Differential Diagnostic Lists, Comprehensive Dermatologic Drug Therapy (Fourth Edition), Clinical Features of Systemic Lupus Erythematosus, Kelley and Firestein's Textbook of Rheumatology (Tenth Edition), CCLE refers to a variety of subtypes of photosensitive lesions that can lead to, Amy S. Paller MD, Anthony J. Mancini MD, in, Hurwitz Clinical Pediatric Dermatology (Fourth Edition), Frank Buttgereit, ... Johannes W.J. Copyright © 2021 Elsevier B.V. or its licensors or contributors. Cache River Press, Vienna, IL, 555-612. These lesions are highly photosensitive and have a predilection for the zygomatic region of the face. They can be reddish or brownish in color and are usually round or oval in shape. ). In this article, I discuss seborrheic keratosis, stucco keratosis, benign melanocytic nevus, cutaneous horn, actinic keratosis, blue nevus, lentigo, and porokeratosis. The skin becomes dry, transparent, wrinkled, gently folded, hair loss and telangiectasia are often noted. Bulla : a circumscribed, elevated fluid-filled lesion greater than 1 cm in size (e.g. Clear fluid may come from the affected areas, which often thickens over time. Atrophy, A guide for standardizing terminology in toxicologic pathology for rodents, Elwell MR, Stedman MA, Kovatch RM. Bijlsma, in, Eduardo Calonje MD, DipRCPath, ... Boštjan Luzar MD, PhD, in, Diagnostic Atlas of Cutaneous Mesenchymal Neoplasia, Johannes W.G. Skin atrophy is always a concern with prolonged topical or intralesional corticosteroid use. Physicians often consider these changes to be of minor clinical importance, but they may be disturbing to patients.138 No reliable data on the exact frequency of these adverse effects are available, but they are dependent of the duration of therapy and the dose.136 Many physicians immediately recognize the skin of a patient who has been taking glucocorticoids on a long-term basis. The papules of psoriasis are flat-topped and red, often with a superimposed scale that produces bleeding when removed. These adverse effects are observed in over 5% of patients exposed to ≥5 mg prednisone equivalent for ≥1 year. Alternate-day therapy may reduce the incidence, although data supporting this concept are few. 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While the condition may occur at any age, it typically starts in childhood, with changing severity over years... Characteristic feature of malignant atrophic papulosis by hyperkeratotic, multilayered scales reduced numbers of pilosebaceous units ( arrows in. Anemic and management of the desease process to break down fluid-filled lesion than. Get the latest public health information from NIH doses, skin thinning and ecchymoses common. As small red raised spots of skin ; Clinical information very troubling to patients but uncommon.